作者: Robert M. Straubinger , Karthik Ramani , Vivek S. Purohit , Sathyamagalam Balasubramanian
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摘要: Methods and composition are described for low immunogenic protein, polypeptide or peptide formulations. The method comprises forming complexes of the with a binding agent which can be serine containing compound other phosphatidyl compounds phospholipids. formed include simple complexes, micelles, cochleate structures, liposomes, non-bilayer novel lipidic structures. antigenicity imminogenicity polypeptides peptides is reduced upon formation such complexes.