Cimetidine in elective Caesarean section

摘要: Summary Aspiration pneumonitis, Mendelson's syndrome, continues to be an important cause of maternal morbidity and mortality in obstetric Anaesthesia, despite widespread adoption the practice routine administration alkalis. Histamine H2 receptor blocking drugs have been shown reduce gastric secretion non-obstetric patients. Cimetidine was given intravenously fasting patients before elective Caesarean section. In all 10 who received cimetidine 200 mg at 60–80 minutes pH contents time induction above 2·5. When interval between drug Anaesthesia only 30–40 (six patients) or over 90 (20 then raised this value two-thirds By contrast eight untreated were found a less than No adverse effects seen mothers infants.