Negative epistasis between the malaria-protective effects of α+-thalassemia and the sickle cell trait
作者： Thomas N Williams , Tabitha W Mwangi , Sammy Wambua , Timothy E A Peto , David J Weatherall
DOI: 10.1038/NG1660
关键词:
摘要: … underlying α + -thalassemia. Negative epistasis could explain the failure of α + -thalassemia … Accordingly, we studied the effects of both HbAS and α + -thalassemia on the epidemiology …
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