A review of clinical trials assessing the efficacy and safety of newer antiarrhythmic drugs in atrial fibrillation.
作者： Gerald V. Naccarelli , Deborah L. Wolbrette , Luna Bhatta , Mazhar Khan , John Hynes
关键词:
摘要: Clinical trials assessing the efficacy of anti- arrhythmic drugs for terminating atrial fibrillation have demonstrated that rate control little to no added compared placebo; however, spontaneous conversion recent-onset is common. Antiarrhythmic such as oral dofetilide, bolus-flecainide and propafenone intravenous ibutilide all a role in fibrillation. Active comparator amiodarone more efficacious maintaining sinus rhythm than sotalol. Multiple safety amiodarone, sotalol, dofetilide azimilide post-myocardial infarction population congestive heart failure population. Newer antiarrhythmic agents, some with novel mechanisms action, will add pharmacologic armamentarium treating
springer.com
elsevier.com
sci-hub.se 参考文章(46)
Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Investigators, None, A comparison of rate control and rhythm control in patients with atrial fibrillation. The New England Journal of Medicine. ,vol. 347, pp. 1825- 1833 ,(2002) , 10.1056/NEJMOA021328
Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF) The Lancet. ,vol. 353, pp. 2001- 2007 ,(1999) , 10.1016/S0140-6736(99)04440-2
J. Paul Mounsey, John P. DiMarco, Cardiovascular drugs. Dofetilide. Circulation. ,vol. 102, pp. 2665- 2670 ,(2000) , 10.1161/01.CIR.102.21.2665
Annabelle S Volgman, Peter A Carberry, Bruce Stambler, William R Lewis, George H Dunn, Kimberly T Perry, James T VanderLugt, Peter R Kowey, Conversion efficacy and safety of intravenous ibutilide compared with intravenous procainamide in patients with atrial flutter or fibrillation. Journal of the American College of Cardiology. ,vol. 31, pp. 1414- 1419 ,(1998) , 10.1016/S0735-1097(98)00078-3
Edward L.C. Pritchett, William E. Wilkinson, Walter K. Clair, Elizabeth A. McCarthy, Comparison of mortality in patients treated with propafenone to those treated with a variety of antiarrhythmic drugs for supraventricular arrhythmias American Journal of Cardiology. ,vol. 72, pp. 108- 110 ,(1993) , 10.1016/0002-9149(93)90231-Z
HernanC Doval, DanielR Nul, HugoO Grancelli, SergioV Perrone, GuillermoR Bortman, Rodolfo Curiel, Randomised trial of low-dose amiodarone in severe congestive heart failure The Lancet. ,vol. 344, pp. 493- 498 ,(1994) , 10.1016/S0140-6736(94)91895-3
Giuseppe Boriani, Mauro Biffi, Alessandro Capucci, Gian Luca Botto, Tiziana Broffoni, Ida Rubino, Stefano Della Casa, Mario Sanguinetti, Bruno Magnani, Oral Propafenone To Convert Recent-Onset Atrial Fibrillation in Patients with and without Underlying Heart Disease: A Randomized, Controlled Trial Annals of Internal Medicine. ,vol. 126, pp. 621- 625 ,(1997) , 10.7326/0003-4819-126-8-199704150-00006
Matti O. Halinen, Matti Huttunen, Seija Paakkinen, Leo Tarssanen, Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the sotalol-digoxin-quinidine trial) The American Journal of Cardiology. ,vol. 76, pp. 495- 498 ,(1995) , 10.1016/S0002-9149(99)80137-4
Isabelle C. Van Gelder, Vincent E. Hagens, Hans A. Bosker, J. Herre Kingma, Otto Kamp, Tsjerk Kingma, Salah A. Said, Julius I. Darmanata, Alphons J.M. Timmermans, Jan G.P. Tijssen, Harry J.G.M. Crijns, A comparison of rate control and rhythm control in patients with recurrent persistent atrial fibrillation The New England Journal of Medicine. ,vol. 347, pp. 1834- 1840 ,(2002) , 10.1056/NEJMOA021375
Wei Sun, Jonnalagedda S. M. Sarma, Bramah N. Singh, Electrophysiological effects of dronedarone (SR33589), a noniodinated benzofuran derivative, in the rabbit heart : comparison with amiodarone. Circulation. ,vol. 100, pp. 2276- 2281 ,(1999) , 10.1161/01.CIR.100.22.2276