Chromosome abnormalities, clinical and morphological manifestations in metamorphosis of chronic myeloid leukemia.
作者： Éva Oläh , Attila Kiss , János Jakq
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摘要: Seventeen cases of chronic myeloid leukemia (CML) in metamorphosis have been investigated by cytogenetic methods. Six patients were studied slow transformation and others the terminal blastic phase disease. Of these, 3 myeloid, 3 myelomonocytic, 1 megakaryoblastic, promyelocytic 4 lymphoid their morphological cytochemical appearance. Some correlation could be observed between clinical, morphological, and cytogenetic findings different subgroups. The results demonstrate the importance chomosome investigations early diagnosis metamorphosis and distinguishing subgroups stage CML.
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