Use of a modified rev-responsive element (rre) in methods and compositions for combatting hiv infection
作者： Peter Jonathan Gasking Butler , Jonathan Karn , Rodney Warren Zemmel , Alistair Simpson Irvine , Roger Kingdon Craig
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摘要: The invention relates to an isolated nucleic acid comprising two operatively linked binding sites for HIV Rev protein, the a nucleation motif and oligomerization motif, wherein binds protein monomers with higher degree of co-operativity than wild-type RRE.
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