Natural products as potential cancer therapy enhancers: A preclinical update.

摘要: Cancer is a multifactorial disease that arises as consequence of alterations in many physiological processes. Recently, hallmarks cancer were suggested include sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, and activating invasion metastasis, along with two emerging including reprogramming energy metabolism escaping immune destruction. Treating diseases, such agents targeting single target, might provide partial treatment and, cases, disappointing cure rates. Epidemiological studies have consistently shown the regular consumption fruits vegetables strongly associated reduced risk developing chronic cardiovascular diseases cancer. Since ancient times, plants, herbs, other natural products been used healing agents. Moreover, majority medicinal substances available today their origin compounds. Traditionally, pharmaceuticals are to nutrition herbs prevent an optimal balance macro- micro-nutrients needed for good health. We explored combination products, dietary nutrition, chemotherapeutics improving efficacy negating side effects.