作者: Benjamin Nota , Martijn J.T.N. Timmermans , Oscar Franken , Kora Montagne-Wajer , Janine Mariën
DOI: 10.1021/ES801472R
关键词:
摘要: Increasing concern about pollution of our environment calls for advanced and rapid methods to estimate ecological toxicity. The use gene expression microarrays in environmental studies can potentially meet this challenge. We present a novel method examine soil exposed the collembolan Folsomia candida containing an ecologically relevant cadmium concentration, found cumulative total 1586 differentially expressed transcripts across three exposure durations, including involved stress response, detoxification, hypoxia. Additional enrichment analysis ontology (GO) terms revealed that antibiotic biosynthesis is important at all time points examined. Interestingly, genes "penicillin cephalosporin pathway" have never been identified animals before, but are F. candida's tissue. synthesis antibiotics possibly be response increased cadmium-induced susceptibility invading pathogens, which might caused by repression immune-system (C-type lectins Toll receptor). This study presents first global view on arthropod species contaminated soil, provides mechanistic basis development quality test.