The Koch Phenomenon and the Immunopathology of Tuberculosis

作者: G. A. W. Rook , J. L. Stanford

DOI: 10.1007/978-3-642-80166-2_11

关键词:

摘要: Tuberculosis kills more than three million people every year, and the problem is rapidly increasing. This paradoxical when we know that immune response perfectly capable of coping with this infection. Before advent HIV, only 5% infected individuals developed disease, perhaps another did so T cell function was compromised by old age, stress or protein malnutrition. Therefore 90% population resistant under normal circumstances. Moreover incidence in suceptible 10% could be reduced up to 80% BCG vaccination those countries which vaccine worked. Why then are failing control rapid increase tuberculosis?

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