Effect of mean platelet volume on postintervention coronary blood flow in patients with chronic stable angina pectoris.

摘要: OBJECTIVES In our study we sought to determine whether mean platelet volume (MPV), measured on admission, could be used in determining decreased coronary blood flow (CBF) stable artery disease (CAD) patients after percutaneous intervention (PCI). BACKGROUND Platelets play a crucial role the pathophysiology of CAD. MPV reflects function and activity. There are no reports regarding effect CBF with CAD undergoing PCI. METHODS A total 66 consecutive (mean age: 58 +/- 5 years, 74% male) diagnosis who were hospitalized for PCI prospectively enrolled study. Coronary rates all subjects documented by corrected thrombolysis myocardial infarction (TIMI) frame count (CTFC) each major before Blood samples estimation, other laboratory data obtained admission day scheduled Patients divided into two groups according levels admission: 1) high group 2) normal group. RESULTS final TIMI 3 was achieved complications. Procedural characteristics PCI, except left anterior descending intervention, similar groups. had significantly higher CTFC than those (24 vs. 17 5; p = 0.001). The correlated strongly post-PCI (R 0.625; 0.0001). Multiple logistic regression analysis showed that only an independent predictor adjustment baseline (OR 1.9, 95% CI 1.2-2.3; CONCLUSIONS may considered useful hematological marker, allowing early easy identification at risk low-reflow.