Why all blood donations should be tested for hepatitis E virus (HEV)

摘要: Hepatitis E is a liver disease caused by small RNA virus known as hepatitis (HEV). Four major genotypes infect humans, of which genotype 1 and 2 (HEV-1, HEV-2) are endemic mainly in Asia responsible for waterborne epidemics. HEV-3 HEV-4 widely distributed pigs can be transmitted to humans undercooked meat, contact with pigs. the main industrialised countries moderate climate conditions object this debate. Whereas an infection healthy mostly asymptomatic, induce chronic immunocompromised individuals acute-on-chronic failure (ACLF) patients underlying diseases. The number reported cases HEV-infections nations increased significantly last years. Since has been blood transfusion other testing donors introduced or introduction being discussed some countries. In article we summarise arguments favour all donations HEV-3. HEV population possibility transmission increasing. Transmission dangerous recipients considering their immunosuppressive status, circumstances requiring transfusion. This argues prevent transmission.