Can a Silent Kidney Infection or Genetic Predisposition Underlie Recurrent UTIs

摘要: Complications resulting from persistent and repeated urinary tract infections (UTIs) account for nearly 1 million hospital admissions annually. Cystitis, a localized bladder infection occurring in the lower tract, is recognized by symptom complex of dysuria, frequency, urgency, suprapubic tenderness; pyelonephritis, which refers to upper kidneys, classically manifests with flank pain systemic as well cystitis signs. An empiric 3-day antibiotic regimen has been shown be more than 95% effective curing cystitis. But subgroup patients, relapse "cystitis" within 4 weeks can signal subclinical, "silent," pyelonephritis. A 14-day course antibiotics indicated treat recurrent UTI. Follow-up urinalysis urine cultures are then 2 after therapy. If symptoms and/or bacteriuria again documented same organism, subclinical pyelonephritis presumed; prolonged 6-week warranted prevent problems complications associated UTIs. When problem reinfection microorganism different that responsible last infection, short-course therapy 3 days may prescribed each episode. occurs frequently times year, however, prophylaxis reinfections warranted.