Tackling antimicrobial resistance in lower urinary tract infections: treatment options.

作者: Johann D Pitout , Wilson W Chan , Deirdre L Church

DOI: 10.1080/14787210.2016.1188004

关键词: FosfomycinNitrofurantoinUrinary tract infection (UTI)Antibiotic resistanceBiologyMicrobiologyPivmecillinamReview articleEtiologyAntibioticsIntensive care medicine

摘要: ABSTRACTIntroduction: Urinary tract infections (UTIs) are among the most common infectious diseases occurring in either community or healthcare settings. A wide variety of bacteria responsible for causing UTIs, however extra-intestinal pathogenic E. coli ExPEC) remains etiological agent. Since 2000, resistance to antibiotics emerged globally ExPEC and is delays appropriate therapy with subsequent increased morbidity mortality.Areas covered: The aim this review article provide an overview on definitions, etiology, treatment guidelines (including agents due antimicrobial resistant bacteria) lower UTIs highlight recent aspects ExPEC.Expert commentary: For patients acute uncomplicated nitrofurantoin, trimethoprim-sulfamethoxazole, fosfomycin pivmecillinam should be prescribed a 1-5 day course depending agent used. Single-dose excellent option f...

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