作者: Johann D Pitout , Wilson W Chan , Deirdre L Church
DOI: 10.1080/14787210.2016.1188004
关键词: Fosfomycin 、 Nitrofurantoin 、 Urinary tract infection (UTI) 、 Antibiotic resistance 、 Biology 、 Microbiology 、 Pivmecillinam 、 Review article 、 Etiology 、 Antibiotics 、 Intensive care medicine
摘要: ABSTRACTIntroduction: Urinary tract infections (UTIs) are among the most common infectious diseases occurring in either community or healthcare settings. A wide variety of bacteria responsible for causing UTIs, however extra-intestinal pathogenic E. coli ExPEC) remains etiological agent. Since 2000, resistance to antibiotics emerged globally ExPEC and is delays appropriate therapy with subsequent increased morbidity mortality.Areas covered: The aim this review article provide an overview on definitions, etiology, treatment guidelines (including agents due antimicrobial resistant bacteria) lower UTIs highlight recent aspects ExPEC.Expert commentary: For patients acute uncomplicated nitrofurantoin, trimethoprim-sulfamethoxazole, fosfomycin pivmecillinam should be prescribed a 1-5 day course depending agent used. Single-dose excellent option f...