Immune-Complex-Mediated Biologic Effects

作者: Roger C. Wiggins , Charles G. Cochrane

DOI: 10.1056/NEJM198102263040904

关键词:

摘要: COMPLEXES of antigen and antibody (immune complexes) are capable causing inflammatory injury.1 Many human diseases can now be attributed to the presence immune complexes in tissues. Some examples systemic lupus erythematosus, acute chronic glomerulonephritis, rheumatoid arthritis, vasculitis, tissue injury associated with a variety infectious agents. Immune formed by union one or more molecules molecules. Once formed, complex may activate cellular humoral mediator systems that cause injury. The means which develop tissues has been determined several experiments. . . .

参考文章(7)
C.G. Cochrane, D. Koffler, Immune Complex Disease in Experimental Animals and Man Advances in Immunology. ,vol. 16, pp. 185- 264 ,(1973) , 10.1016/S0065-2776(08)60298-9
Emil R. Unanue, Frank J. Dixon, Experimental glomerulonephritis: immunological events and pathogenetic mechanisms. Advances in Immunology. ,vol. 6, pp. 1- 90 ,(1967) , 10.1016/S0065-2776(08)60521-0
L G Hunsicker, T P Shearer, S B Plattner, D Weisenburger, The role of monocytes in serum sickness nephritis. Journal of Experimental Medicine. ,vol. 150, pp. 413- 425 ,(1979) , 10.1084/JEM.150.3.413
Stephen R. Holdsworth, T.James Neale, Curtis B. Wilson, The participation of macrophages and monocytes in experimental immune complex glomerulonephritis. Clinical Immunology and Immunopathology. ,vol. 15, pp. 510- 524 ,(1980) , 10.1016/0090-1229(80)90063-X
Charles G. Cochrane, Kirk D. Wuepper, Barbara S. Aiken, Susan D. Revak, Hans L. Spiegelberg, The Interaction of Hageman Factor and Immune Complexes Journal of Clinical Investigation. ,vol. 51, pp. 2736- 2745 ,(1972) , 10.1172/JCI107093
Argyrios N. Theofilopoulos, Frank J. Dixon, The Biology and Detection of Immune Complexes Advances in Immunology. ,vol. 28, pp. 89- 220 ,(1980) , 10.1016/S0065-2776(08)60800-7
Hans J. Müller-Eberhard, COMPLEMENT: MOLECULAR MECHANISMS, REGULATION AND BIOLOGIC FUNCTION12 Molecular Basis of Biological Degradative Processes. pp. 65- 114 ,(1978) , 10.1016/B978-0-12-092150-8.50008-4