Room temperature ionic liquid promoted regioselective synthesis of 2-aryl benzimidazoles, benzoxazoles and benzthiazoles under ambient conditions
作者： R Nadaf
DOI: 10.1016/J.MOLCATA.2003.10.064
关键词:
摘要: A regioselective one-pot synthesis of 2-aryl benzimidazoles, benzoxazoles and benzthiazoles has been achieved in excellent isolated yields under ambient conditions using the ionic liquids, 1-butylimidazolium tetraflouroborate ([Hbim]BF4) 1,3-di-n-butylimidazolium tetrafluoroborate ([bbim]BF4) as reaction media promoters. There was no need for use an additional catalyst normally employed methodologies reported so far.
cheric.org
elsevier.com参考文章(16)
Marc Häring, Zur Darstellung von 1‐Alkylimidazolen aus Imidazol Helvetica Chimica Acta. ,vol. 42, pp. 1845- 1846 ,(1959) , 10.1002/HLCA.19590420612
Devalla V. Ramana, Ethirajulu Kantharaj, Mass spectrometer as a probe in the synthesis of 2-substituted benzimidazoles Tetrahedron. ,vol. 50, pp. 2485- 2496 ,(1994) , 10.1016/S0040-4020(01)86965-9
L.J. Mathias, D. Burkett, N-alkylation of benzimidazoles and benzotriazole via phase transfer catalysis Tetrahedron Letters. ,vol. 20, pp. 4709- 4712 ,(1979) , 10.1016/S0040-4039(01)86690-9
Jason P. Hallett, Tom Welton, Room-Temperature Ionic Liquids. Solvents for Synthesis and Catalysis Chemical Reviews. ,vol. 99, pp. 2071- 2083 ,(1999) , 10.1021/CR1003248
Junichi KONDO, Nobuyuki SUZUKI, Toshi IMAOKA, Takao KAWASAKI, Akio NAKANISHI, Yukinori KAWAHARA, 6-Methoxy-2-(4-substituted phenyl)benzoxazoles as Fluorescent Chiral Derivatization Reagents for Carboxylic Acid Enantiomers. Analytical Sciences. ,vol. 10, pp. 17- 23 ,(1994) , 10.2116/ANALSCI.10.17
Carl S. Marvel, Thermally stable polymers Pure and Applied Chemistry. ,vol. 16, pp. 351- 368 ,(1968) , 10.1351/PAC196816020351
J. H. Brimmell, The Proton in Chemistry Journal of The Electrochemical Society. ,vol. 109, pp. 117C- ,(1962) , 10.1149/1.2425397
William A Denny, Gordon W Rewcastle, Bruce C Baguley, None, Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of "minimal" DNA-intercalating agents which may not act via topoisomerase II. Journal of Medicinal Chemistry. ,vol. 33, pp. 814- 819 ,(1990) , 10.1021/JM00164A054
Peter Wasserscheid, Wilhelm Keim, Ionic Liquids-New "Solutions" for Transition Metal Catalysis. Angewandte Chemie. ,vol. 39, pp. 3772- 3789 ,(2000) , 10.1002/1521-3773(20001103)39:21<3772::AID-ANIE3772>3.0.CO;2-5
Jiajian Peng, Youquan Deng, Catalytic Beckmann rearrangement of ketoximes in ionic liquids Tetrahedron Letters. ,vol. 42, pp. 403- 405 ,(2001) , 10.1016/S0040-4039(00)01974-2