Impact of acute renal failure on mortality in end-stage liver disease with or without transplantation

摘要: Impact of acute renal failure on mortality in end-stage liver disease with or without transplantation. Background Acute (ARF) is traditionally considered a poor prognostic factor and associated approaching 90%. While the increased use orthotopic transplantation (OLTX) has changed outcome for patients (ESLD), it not clear whether this affected ESLD ARF. Methods We prospectively followed course ARF 177 being evaluated OLTX. Of these 111 received In-hospital was compared to that 316 ARF, 196 Variables include severity illness as assessed by APACHE II, co-morbid conditions, oliguria, need replacement therapy, etiologies These variables were respect in-hospital multiple regression analysis Results Mortality significantly higher oliguric versus non-oliguric who required therapy. correlated strongly number especially sepsis, encephalopathy, respiratory failure, DIC. For OLTX recipients developed no significant difference survival occurred pre-OLTX post-OLTX. Conclusion an consistent known adverse effect ESLD. However, remarkably reduced functioning Since expected generated from II scores groups, there additional beyond physiologic derangements captured II. per se should necessarily be contraindication transplant.