作者: Xavier Drouot , Belen Cabello , Marie-Pia d’Ortho , Laurent Brochard
DOI: 10.1016/J.SMRV.2007.11.004
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摘要: Intensive care unit (ICU) environment is not propitious for restoring sleep. Alterations in sleep have potential detrimental consequences explaining increasing interest the field over last years. Methods to study ICU meets some limitations. Accurate analysis requires full polysomnography, but polysomnographic patterns of normal are frequently lacking these patients and conventional scoring rules may be inadequate. Patients experience severe alterations with loss, fragmentation sleep-wake cycle disorganization. Many factors contribute abnormalities, including patient-related (e.g., disease severity) environmental continuous exposure light noise, around-the-clock care, medications). Health support techniques such as mechanical ventilation sedation also disruption. The impact disturbances on morbidity mortality remains unknown inferences from experimental studies or indirect evidence suggest possible immune function neuropsychological dysfunction that could hamper weaning assisted ventilation. Whether disruption independently associated adverse outcomes merely constitutes a marker cerebral determined. However, whatever signification mechanisms alterations, now specific measures recommended protect circadian rhythm ICU.