Does specialized surgical training increase lymph node yield in colon cancer

作者: Michael B. Nicholl , Byron E. Wright , W. Charles Conway , Trista Aarnes-Leong , Myung-Shin Sim

DOI: 10.1177/000313480907501005

关键词:

摘要: Most colon cancer resections do not meet the 12-lymph node minimum recommended in 2001 National Cancer Institute (NCI) panel guidelines. Previous reports suggest surgical training influences lymph recovery. We hypothesized that recent trends show improved results for lymphadenectomy regardless of specialty. The registry database at a large community hospital with an academic oncology program was queried to identify performed before (1995 2000) and after (2001 2006) NCI guideline publication. There were no changes pathology procedures between 374 early 411 later procedures. period brought increases mean total nodes (15.4 vs 10.4, P < 0.0001), positive (1.8 1.2, = 0.005), percentage yielding 12 or more (overall: 65.9 36.0%, 0.0001; Stage II III disease: 73.0 41.4%, 0.003). In addition, nodal yield increased (P 0.0001) fellowship-trained surgeons (16.7 11.2) nonfellowshiptrained (14.9 10.2). Single-registry data since 2001, most exceed recommendations recovery training. rate adequate disease is encouraging because this patient population will benefit by accurate staging cancer.

参考文章(26)
Michelle A. Ostadi, Julie L. Harnish, Stacey Stegienko, David R. Urbach, Factors affecting the number of lymph nodes retrieved in colorectal cancer specimens Surgical Endoscopy. ,vol. 21, pp. 2142- 2146 ,(2007) , 10.1007/S00464-007-9414-6
Natalie E Joseph, Elin R Sigurdson, Alexandra L Hanlon, Hao Wang, Robert J Mayer, John S MacDonald, Paul J Catalano, Daniel G Haller, None, Accuracy of determining nodal negativity in colorectal cancer on the basis of the number of nodes retrieved on resection. Annals of Surgical Oncology. ,vol. 10, pp. 213- 218 ,(2003) , 10.1245/ASO.2003.03.059
P Johnson, Adequacy of Nodal Harvest in Colorectal Cancer: A Consecutive Cohort Study☆ Journal of Gastrointestinal Surgery. ,vol. 6, pp. 883- 890 ,(2002) , 10.1016/S1091-255X(02)00131-2
Anton J Bilchik, Dave SB Hoon, Sukamal Saha, Roderick R Turner, David Wiese, Maggie DiNome, Kazuo Koyanagi, Martin McCarter, Perry Shen, Douglas Iddings, Steven L Chen, Maria Gonzalez, David Elashoff, Donald L Morton, None, Prognostic impact of micrometastases in colon cancer: interim results of a prospective multicenter trial. Annals of Surgery. ,vol. 246, pp. 568- 577 ,(2007) , 10.1097/SLA.0B013E318155A9C7
Thomas E. Read, Robert J. Myerson, James W. Fleshman, Robert D. Fry, Elisa H. Birnbaum, Bruce J. Walz, Ira J. Kodner, Surgeon specialty is associated with outcome in rectal cancer treatment. Diseases of The Colon & Rectum. ,vol. 45, pp. 904- 914 ,(2002) , 10.1007/S10350-004-6327-5
G. J. Chang, M. A. Rodriguez-Bigas, J. M. Skibber, V. A. Moyer, Lymph Node Evaluation and Survival After Curative Resection of Colon Cancer: Systematic Review Journal of the National Cancer Institute. ,vol. 99, pp. 433- 441 ,(2007) , 10.1093/JNCI/DJK092
WARREN E. ENKER, URBAN TH. LAFFER, GEORGE E. BLOCK, Enhanced survival of patients with colon and rectal cancer is based upon wide anatomic resection. Annals of Surgery. ,vol. 190, pp. 350- 360 ,(1979) , 10.1097/00000658-197909000-00010
Anton J. Bilchik, Dean T. Nora, Leslie H. Sobin, Roderick R. Turner, Steven Trocha, David Krasne, Donald L. Morton, Effect of Lymphatic Mapping on the New Tumor-Node-Metastasis Classification for Colorectal Cancer Journal of Clinical Oncology. ,vol. 21, pp. 668- 672 ,(2003) , 10.1200/JCO.2003.04.037
Brian M. Wolpin, Robert J. Mayer, Systemic Treatment of Colorectal Cancer Gastroenterology. ,vol. 134, pp. 1296- 1310.e1 ,(2008) , 10.1053/J.GASTRO.2008.02.098
Hsiang-Lin Tsai, Chien-Yu Lu, Jan-Sing Hsieh, Deng-Chyang Wu, Chang-Ming Jan, Chee-Yin Chai, Koung Shing Chu, Hon-Man Chan, Jaw-Yuan Wang, The prognostic significance of total lymph node harvest in patients with T2-4N0M0 colorectal cancer. Journal of Gastrointestinal Surgery. ,vol. 11, pp. 660- 665 ,(2007) , 10.1007/S11605-007-0119-X