Racial and ethnic differences in lymph node examination after colon cancer resection do not completely explain disparities in mortality.

作者: Kim F. Rhoads , Jennifer Cullen , Justine V. Ngo , Sherry M. Wren

DOI: 10.1002/CNCR.26316

关键词:

摘要: BACKGROUND: In 1999, a multidisciplinary panel of experts in colorectal cancer reviewed the relevant medical literature and issued consensus recommendation for 12-lymph node (LN) minimum examination after resection colon cancer. Some authors have shown racial/ethnic differences receipt this evidence-based care. To date, however, none has investigated correlation between disparities LN outcomes treatment. METHODS: This retrospective analysis used California Cancer Registry linked to Office Statewide Health Planning Development discharge data (1996-2006). Chi-square analysis, logistic regression, Cox proportional hazard models predicted an adequate effect inadequate exam on mortality disparities. Patients with stage I II cancers undergoing surgery were included; patients III IV disease excluded. RESULTS: A total 37,911 records analyzed. Adequate staging occurred fewer than half cases. An (<12 LNs) was associated higher rates. Hispanics had lowest odds receiving exam; blacks, not Hispanics, highest risk compared whites. This disparity completely explained by examination. CONCLUSIONS: Inadequate occurs often is increased mortality. There are exam, but only explains small part observed Improving quality alone unlikely correct 2011;. © 2011 American Society.

参考文章(54)
Michael B. Nicholl, Byron E. Wright, W. Charles Conway, Trista Aarnes-Leong, Myung-Shin Sim, Mark B. Faries, Does specialized surgical training increase lymph node yield in colon cancer American Surgeon. ,vol. 75, pp. 887- 891 ,(2009) , 10.1177/000313480907501005
Sherry Weitzen, Christina A. Raker, Elisabeth A. Erekson, Deborah L. Myers, Vivian W. Sung, Socioeconomic Indicators and Hysterectomy Status in the United States, 2004 Journal of Reproductive Medicine. ,vol. 54, pp. 553- 558 ,(2009)
Timothy M. McCashland, Julia Gore Thornton, Arden M. Morris, Christopher R. Flowers, John Daryl Thornton, Racial variation in colorectal polyp and tumor location. Journal of The National Medical Association. ,vol. 99, pp. 723- 728 ,(2007)
Nancy Krieger, Charles Quesenberry Jr, Tiffany Peng, Pamela Horn-Ross, Susan Stewart, Susan Brown, Karen Swallen, Tessie Guillermo, Dong Suh, Luz Alvarez-Martinez, Felicia Ward, Social class, race/ethnicity, and incidence of breast, cervix, colon, lung, and prostate cancer among Asian, Black, Hispanic, and White residents of the San Francisco Bay Area, 1988-92 (United States). Cancer Causes & Control. ,vol. 10, pp. 525- 537 ,(1999) , 10.1023/A:1008950210967
Baqar A. Husaini, Nathaniel C. Briggs, Van A. Cain, Bojuan B. Zhao, Robert Levine, Barbara Kilbourne, Steven C. Stain, Racial Disparities and Trends in Use of Colorectal Procedures Among Tennessee Elderly (1996-2000) Ethnicity & Disease. ,vol. 16, pp. 412- 420 ,(2006) , 10.13016/VF8T-SCUS
Vickie L. Shavers, Linda C. Harlan, Deborah Winn, William W. Davis, Racial/ethnic patterns of care for cancers of the oral cavity, pharynx, larynx, sinuses, and salivary glands. Cancer and Metastasis Reviews. ,vol. 22, pp. 25- 38 ,(2003) , 10.1023/A:1022255800411
Kathleen Yost, Carin Perkins, Richard Cohen, Cyllene Morris, William Wright, Socioeconomic status and breast cancer incidence in California for different race/ethnic groups. Cancer Causes & Control. ,vol. 12, pp. 703- 711 ,(2001) , 10.1023/A:1011240019516
U. Metzger, Adjuvant therapy for colon and rectal cancer. NIH Consensus Development Conference. European Journal of Cancer and Clinical Oncology. ,vol. 26, pp. 753- 755 ,(1990) , 10.1016/0277-5379(90)90136-H
Michelle A. Ostadi, Julie L. Harnish, Stacey Stegienko, David R. Urbach, Factors affecting the number of lymph nodes retrieved in colorectal cancer specimens Surgical Endoscopy. ,vol. 21, pp. 2142- 2146 ,(2007) , 10.1007/S00464-007-9414-6
Isac S. F. Lima, Yutaka Yasui, Andrew Scarfe, Marcy Winget, Association between receipt and timing of adjuvant chemotherapy and survival for patients with stage III colon cancer in Alberta, Canada Cancer. ,vol. 117, pp. 3833- 3840 ,(2011) , 10.1002/CNCR.25954