Paradigms to Study Signal Transduction Pathways in Drosophila

摘要: Publisher Summary This chapter discusses the mechanisms, by which groups of cells alter developmental behavior other during oogenesis and embryogenesis. It describes processes embryogenesis in Drosophila melanogaster , how various genetic analyses have led to characterizations genes involved specific cell-cell interaction processes. Signaling pathways employed are strikingly similar those vertebrates, so these paradigms clearly valuable model systems analyze evolutionarily conserved signaling pathways. These can be used for “gene discovery” subsequent identification mammalian homologues novel components identified from studies. Furthermore, as vivo assays test hypotheses drawn biochemical The examples described this provide simple identify that operate dissect details signals transduced. also some molecular build egg pattern embryo. unique apply tools characterize their functions.