pH- and photo-switched release of guest molecules from mesoporous silica supports.

摘要: This paper proposes a new nanoscopic molecular movable gate-like functional hybrid system consisting of MCM-41-based material functionalized onto pore outlets with saccharide derivative capable interacting boronic acid gold nanoparticles (AuNPs) acting as caps. The gating mechanism involves the reversible reaction between polyalcohols and acids to form boronate esters. Functionalized AuNPs thus act suitable cap via formation corresponding boroester bonds anchored on external surface mesoporous silica-based solid. developed platform operates in aqueous solution can be triggered by two simple stimuli such pH changes or light. hydrolysis bond takes place at 3, which results rapid delivery safranine cargo from voids into solution. However, 5 pores are capped is strongly inhibited. kinetics was studied = assuming diffusion process that guest release explained Higuchi model. It possible deliver small portions carrying out on-off aperture cycles changing 3 5. also open possibility employing light stimulus for procedures using AuNPs' capacity raising their temperature locally absorption laser plasmonic heating Nd:YAG 1064 nm cleavage ester linkage anchors material, allowing entrapped guests. Further studies demonstrated it fine-tune amount delivered simply controlling irradiation opening designing laser-induced pulsatile supports.