Prevention of perinatal hepatitis B virus transmission in the Netherlands, 2003-2007: children of Chinese mothers are at increased risk of breakthrough infection.
作者： Susan Hahné , Anneke van den Hoek , Dorothé Baayen , Marianne van der Sande , Hester de Melker
DOI: 10.1016/J.VACCINE.2011.12.071
关键词:
摘要: Abstract Background In the Netherlands, different hepatitis B vaccination schedules have been used for children born to HBV-infected mothers. All included a birth dose of immunoglobuline (HBIg). We assessed determinants perinatal HBV transmission and anti-HBs titers in infants HBsAg positive Methods infected mothers between 1.1.2003 30.6.2007, using national databases separate database Amsterdam. Risk factors titer were studied logistic linear regression, respectively. Results Of 2657 registered database, 91% received HBIg at least three vaccinations. Amsterdam, this coverage among 413 risk was higher (96%, p Conclusions Infants Chinese increased infection. pregnant women origin should be determine whether there is an indication anti-viral treatment during pregnancy. Among who birth, we did not detect infection when first vaccine administered after week life.
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