Correlation between Cyclin Dependent Kinases and Artemisinin-Induced Dormancy in Plasmodium falciparum In Vitro

作者: Karen-Ann Gray , Karryn J. Gresty , Nanhua Chen , Veronica Zhang , Clare E. Gutteridge

DOI: 10.1371/JOURNAL.PONE.0157906

关键词:

摘要: Background Artemisinin-induced dormancy provides a plausible explanation for recrudescence following artemisinin monotherapy. This phenomenon shares similarities with cell cycle arrest where cyclin dependent kinases (CDKs) and cyclins play an important role.

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