作者: Srikanth Vedamoorthy , Lingchun Zeng , Min Mo , Joseph D. Kittle , Thomas J. Zupancic
DOI:
关键词:
摘要: A system, device, and method for rapid detection of analytes that includes a living, engineered biosensor cell is typically component the mammalian immune system; reporter protein into expressed by cell, wherein emits detectable signal in response to certain predetermined changes cytosol cell; transduction pathway controls biological process within biochemical process, when it occurs, causes emit signal; at least one type detector molecule adapted bind specific analyte; analyte binds plurality non-antibody transducing elements are either or actively receptor each element receive molecule.