In vitro neo-cartilage formation on a three-dimensional composite polymeric cryogel matrix
作者： Sumrita Bhat , Lars Lidgren , Ashok Kumar
关键词:
摘要: Limited blood supply and the avascular nature of articular cartilage restricts its self repair capacity, frequently leading to osteoarthritis. This work focuses on scaffolds for tissue from natural polymers, example gelatin, chitosan, agarose in form composite. A novel way fabrication, known as cryogelation, is presented, which matrices are synthesized at sub-zero temperature. Cell seeded incubated under appropriate conditions result accumulation matrix components surface gel neo-cartilage. Neo-cartilage exhibits similarity native with respect physical, mechanical biochemical properties. Based similarities neo-cartilage cartilage, it can provide a new approach treatment localised joint injuries.
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