Serotonin transporter polymorphisms (5-HTTLPR) in emotion processing
作者： R. Jonassen , N.I. Landrø
DOI: 10.1016/J.PNEUROBIO.2014.02.003
关键词:
摘要: The candidate gene approach directly tests the effects of genetic variation within a potentially contributing in an association study. However, is limited by how much known about biology disease being investigated. serotonin transporter SLC6A4 has been studied more than any other single field neurobiology. Transcription modulated polymorphic region, 5-HTTLPR, near promoter. 5-HTTLPR genotype associated with individual emotion processing, brain structure, and function. We present updated review biological literature on polymorphism. Recent imaging behavioral studies role processing are discussed light new findings related to variation. also examine clinical implications discoveries neural plasticity malleability.
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