Nosocomial infections and antimicrobial resistance in critical care medicine

摘要: Objective: To review the human and companion animal veterinary literature on nosocomial infections antimicrobial drug resistance as they pertain to critically ill patient. Data sources: Data from sources were reviewed using PubMed CAB. Human data synthesis: There is a large amount of published nosocomially-acquired bloodstream infections, pneumonia, urinary tract surgical site strategies minimize frequency these in medicine. Nosocomial caused by multi-drug-resistant (MDR) pathogens are leading cause increased patient morbidity mortality, medical treatment costs, prolonged hospital stay. Epidemiology risk factor analyses have shown that major for development patients heavy antibiotic usage. Veterinary paucity information small patients. Mechanisms universal, although selection effects created usage may be less significant Future studies animals benefit research has been conducted humans. Conclusions: Antimicrobial use selects MDR pathogens. The choice antimicrobials should prudent based regular surveillance accurate microbiological diagnostics. becoming an increasing problem medicine, particularly critical care setting, institution-specific developed prevent emergence infections. collation tertiary-care hospitals identify trends patterns aid formulating guidelines use.