A promising peptide antibiotic from Terfezia claveryi aqueous extract against Staphylococcus aureus in vitro.

作者: S. Janakat , S. Al-Fakhiri , A.-K. Sallal

DOI: 10.1002/PTR.1563

关键词:

摘要: The antimicrobial activity of aqueous and methanolic extracts, as well partially purified proteins extracted from Terfezia claveryi extract were investigated against Staphylococcus aureus in vitro. A 5% inhibited the growth S. by 66.4%, while a was ineffective. Partial protein purification using ammonium sulphate precipitation revealed that within third fraction. This fraction then subjected to gel filtration Sephadex G-100. Two peaks obtained. Peak one possessed higher activity. peak ion exchange chromatography DEAE Sephadex. Only 4 six obtained showed slight Antimicrobial activities fractions compared with reference antibiotics.

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