Major Bleeding Complications in a Specialized Anticoagulation Service
作者： John Fanikos , Nicole Grasso-Correnti , Ravi Shah , Nils Kucher , Samuel Z. Goldhaber
DOI: 10.1016/J.AMJCARD.2005.03.104
关键词:
摘要: Major bleeding complications were investigated in 2,460 patients with 3,684 patient-years of warfarin exposure from 2000 to 2003. The most common indications for anticoagulation atrial fibrillation (30%), venous thromboembolic disease (28%), and mechanical heart valve prosthesis (15%). Eleven had 12 nonfatal major complications, no fatal bleeds during the study. incidence was 0.12%/year; there 0.32 bleeds/100 coverage. Of events, 5 (42%) intracranial hemorrhages. average hospitalization cost per patient $15,988, length 6.0 days.
elsevier.com
sci-hub.se 参考文章(20)
Emanuele Cecchi, Gian Franco Gensini, Emilia Antonucci, Isabella Corsini, Rosanna Abbate, Domenico Prisco, Daniela Poli, Alessandra Lombardi, Low incidence of hemorrhagic complications of oral anticoagulant therapy in patients with atrial fibrillation in the daily practice of an anticoagulation clinic. Italian heart journal: official journal of the Italian Federation of Cardiology. ,vol. 4, pp. 44- 47 ,(2003)
S Cortelazzo, G Finazzi, P Viero, M Galli, A Remuzzi, L Parenzan, T Barbui, Thrombotic and hemorrhagic complications in patients with mechanical heart valve prosthesis attending an anticoagulation clinic. Thrombosis and Haemostasis. ,vol. 69, pp. 316- 320 ,(1993) , 10.1055/S-0038-1651604
James D. Douketis, Lori-Ann Linkins, Peter T. Choi, Clinical Impact of Bleeding in Patients Taking Oral Anticoagulant Therapy for Venous Thromboembolism Annals of Internal Medicine. ,(2003)
Rebecca J. Beyth, A Multicomponent Intervention To Prevent Major Bleeding Complications in Older Patients Receiving Warfarin Annals of Internal Medicine. ,vol. 133, pp. 687- 695 ,(2000) , 10.7326/0003-4819-133-9-200011070-00010
Stephan D Fihn, Mary McDonell, Donald Martin, Jorja Henikoff, Domokos Vermes, Daniel Kent, Richard H White, Warfarin Optimized Outpatient Follow-up Study Group*, Risk Factors for Complications of Chronic Anticoagulation: A Multicenter Study Annals of Internal Medicine. ,vol. 118, pp. 511- 520 ,(1993) , 10.7326/0003-4819-118-7-199304010-00005
S.C. Cannegieter, F.R. Rosendaal, A.R. Wintzen, F.J.M. van der Meer, J.P. Vandenbroucke, E. Briet, Optimal Oral Anticoagulant Therapy in Patients with Mechanical Heart Valves New England Journal of Medicine. ,vol. 333, pp. 11- 17 ,(1995) , 10.1056/NEJM199507063330103
Sophia Koo, Nils Kucher, Paul L. Nguyen, John Fanikos, Peter W. Marks, Samuel Z. Goldhaber, The Effect of Excessive Anticoagulation on Mortality and Morbidity in Hospitalized Patients With Anticoagulant-Related Major Hemorrhage Archives of Internal Medicine. ,vol. 164, pp. 1557- 1560 ,(2004) , 10.1001/ARCHINTE.164.14.1557
David B Matchar, Gregory P Samsa, Stuart J Cohen, Eugene Z Oddone, Annette E Jurgelski, Improving the quality of anticoagulation of patients with atrial fibrillation in managed care organizations: results of the managing anticoagulation services trial The American Journal of Medicine. ,vol. 113, pp. 42- 51 ,(2002) , 10.1016/S0002-9343(02)01131-2
Elaine M. Hylek, Risk Factors for Intracranial Hemorrhage in Outpatients Taking Warfarin Annals of Internal Medicine. ,vol. 120, pp. 897- 902 ,(1994) , 10.7326/0003-4819-120-11-199406010-00001
C.Seth Landefeld, Rebecca J. Beyth, Anticoagulant-related bleeding: Clinical epidemiology, prediction, and prevention The American Journal of Medicine. ,vol. 95, pp. 315- 328 ,(1993) , 10.1016/0002-9343(93)90285-W