The G401 cell line, utilized for studies of chromosomal changes in Wilms' tumor, is derived from a rhabdoid tumor of the kidney.

摘要: The histology, ultrastructure, and messenger RNA expression of heterotransplants derived from the G401 cell line (American Type Culture Collection) have been characterized by comparison with Wilms' rhabdoid tumors kidney. This analysis illustrates that properties heterotransplant were consistent a phenotype rather than tumor. has utilized in recent experiments to demonstrate central role chromosome 11 However, present results suggest these may be more relevant define involvement tumor kidney, malignancy distinct is clinically since kidney very aggressive associated an extremely poor prognosis.