Orthotopic Wilms tumor xenografts derived from cell lines reflect limited aspects of tumor morphology and clinical characteristics
作者： Linda Holmquist Mengelbier , Daniel Bexell , Daniel Sehic , Cristina D. Ciornei , David Gisselsson
DOI: 10.1002/PBC.25131
关键词:
摘要: Wilms tumor (WT) is a pediatric of the kidney, treatment which includes heavy chemotherapy. Affected children would likely benefit from more targeted therapies with limited side effects. Establishment relevant orthotopic WT xenografts important to better understand mechanisms growth and for preclinical drug testing.
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