TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling
作者： Jan C Brase , Marc Johannes , Heiko Mannsperger , Maria Fälth , Jennifer Metzger
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摘要: Background TMPRSS2-ERG gene fusions occur in about 50% of all prostate cancer cases and represent promising markers for molecular subtyping. Although TMPRSS2-ERG fusion seems to be a critical event cancer, the precise functional role development progression is still unclear.
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