Staphylococcal scalded-skin syndrome in an adult due to methicillin-resistant Staphylococcus aureus

作者: Yoichiro Ito , Katsuhisa Toda , Makoto Shimazaki , Toshiyuki Nakamura , Miyuki Funabashi Yoh

DOI: 10.1007/S10156-002-0175-9

关键词:

摘要: We report a case of 71-year-old man with staphylococcal scalded-skin syndrome (SSSS). The patient, chronic history diabetes mellitus, was admitted to our hospital lumbago, and diagnosis renal-cell carcinoma bone metastasis made. In he had sudden onset high fever erythema, followed by the formation flaccid bullae exfoliation, positive Nikolsky sign. Methicillin-resistant Staphylococcus aureus (MRSA), producing exfoliative toxin B, isolated from blood bile cultures, Aeromonas hydrophila culture. Skin biopsy specimen showed cleavage epidermis at level granular layer. patient diagnosed as having SSSS cholecystitis, treated intravenous antibiotics percutaneous transhepatic gallbladder drainage, which led recovery. in adults is usually associated immunosuppression. A. recognized an opportunistic pathogen. should be considered differential immunocompromised adult patients erythema.

参考文章(48)
J. E. Blair, R. E. O. Williams, Phage typing of staphylococci Bulletin of The World Health Organization. ,vol. 24, pp. 771- 784 ,(1961)
P. K. Peterson, M. Laverdiere, L. D. Sabath, P. G. Quie, Abnormal neutrophil chemotaxis and T-lymphocyte function in staphylococcal scalded skin syndrome in an adult patient. Infection. ,vol. 5, pp. 128- 131 ,(1977) , 10.1007/BF01639745
Shelley, Shelley, Talanin, Chronic staphylococcal scalded skin syndrome. British Journal of Dermatology. ,vol. 139, pp. 319- 324 ,(1998) , 10.1046/J.1365-2133.1998.02376.X
S. Ladhani, Staphylococcal toxins and the scalded skin syndrome British Journal of Dermatology. ,vol. 142, pp. 195- 196 ,(2000) , 10.1046/J.1365-2133.2000.03279.X
Bernard Cribier, Yves Piemont, Edouard Grosshans, Staphylococcal scalded skin syndrome in adults : a clinical review illustrated with a new case Journal of The American Academy of Dermatology. ,vol. 30, pp. 319- 324 ,(1994) , 10.1016/S0190-9622(94)70032-X
G.K. Patel, S. Varma, A.Y. Finlay, Staphyloccocal scalded skin syndrome in healthy adults British Journal of Dermatology. ,vol. 142, pp. 1253- 1255 ,(2000) , 10.1046/J.1365-2133.2000.03571.X
Hideaki Uchino, Takao Shimanuki, Shinishi Ansai, Shigeru Arai, Chiharu Nakamura, Staphylococcal scalded skin syndrome with prosthetic valve endocarditis European Journal of Dermatology. ,vol. 10, pp. 630- 632 ,(2000)
S M Opal, A D Johnson-Winegar, A S Cross, Staphylococcal scalded skin syndrome in two immunocompetent adults caused by exfoliatin B-producing Staphylococcus aureus. Journal of Clinical Microbiology. ,vol. 26, pp. 1283- 1286 ,(1988) , 10.1128/JCM.26.7.1283-1286.1988
JOHN A. WASHINGTON, Aeromonas hydrophila in Clinical Bacteriologic Specimens Annals of Internal Medicine. ,vol. 76, pp. 611- 614 ,(1972) , 10.7326/0003-4819-76-4-611
Richard Rothenberg, Francis S Renna, Thomas M Drew, David S Feingold, Staphylococcal Scalded Skin Syndrome in an Adult Archives of Dermatology. ,vol. 108, pp. 408- 410 ,(1973) , 10.1001/ARCHDERM.1973.01620240058017