Chapter 3 The mitochondrial respiratory chain

摘要: Publisher Summary This chapter offers information on the mitochondrial respiratory chain. A chain is a good collective description of catalysts respiration that transfer reducing equivalents in very specific and functionally chain-like sequence from hydrogen-donating substrates to dioxygen. The composed three catalytic complexes—namely, NADH: ubiquinone (Q) oxidoreductase (Complex I), ubiquinol: ferricytochrome c III), ferrocytochrome :O 2 IV), plus two lower molecular weight redox carriers, cytochrome ubiquinone-10 (Q). Cytochrome carries electrons bc 1 complex, but also auxiliary enzymes oxidase. Ubiquinone only nonprotein member highly hydrophobic substituted benzoquinone collects various dehydrogenases, carrying them complex. has functions within latter All complexes are typical integral membrane proteins span inner membrane. Each comprises several different subunits, exact number which still under debate. genes some subunits oxidase complex DNA (mtDNA).