Self-reported sleep disturbance in patients with advanced cancer: Frequency, intensity, and factors associated with response to outpatient supportive care consultation — A preliminary report

摘要: Objectives Self-reported sleep disturbance (SD) is a distressing symptom in patients with advanced cancer. There are limited data on the treatment of SD and predictors to response outpatient supportive care clinic (OPC) consultation. The aims our study was determine frequency, intensity, correlates as assessed Edmonton Symptom Assessment System (ESAS) item at time initial consultation identify improvement follow-up. Methods We reviewed records consecutive cancer presenting OPC. ESAS scores were obtained subsequent visits between January 2008 February 2010. All underwent screening for (0-10 scale: 0 = best sleep, presence defined ≥ 3) interdisciplinary assessment treatment, including drug review, counseling, hygiene therapy. A 1-point follow-up visit Scale score. Baseline patient characteristics, medication use, analyzed their association response. Results median age 58 years, 53% men. most common type head neck or lung (36%). Of 442 patients, 330 had baseline (score 3/10, 75%). Median mean (standard deviation) 5 5.1 (2.9). multivariable regression model found intensity be associated sedative pain scores, fatigue feeling well-being use (R 2 0.22). Sleep first seen 196 (59%). Moderate high score anxiety odds ratios (OR) 2.53 (p 0.0007) 1.59 0.048), respectively, Significance results Both frequency severity high. Response substantial. predicted Further research needed.