Psychiatric and psychosocial disorders in patients with systemic lupus erythematosus: a longitudinal study of active and inactive stages of the disease.

摘要: The objective was to analyze psychiatric disorders and psychosocial dysfunction in patients with systemic lupus erythematosus (SLE), studied longitudinally during active subsequent inactive stage of their disease. During a 6 month period study, we selected 20 consecutive SLE who presented flare. All fulfilled the 1982 revised criteria American College Rheumatology for classification SLE. When entered performed (CIS, RDC, STAI, HD, BDI, GHQ MMS) (GAS VAS-P) scores assessment. One year later, repeated assessment when showed evaluated were women, mean age 34 y (SE 14.4, range 20-57). According CIS evaluation, diagnosed 8 (40%) cases acute episode RDC diagnosis generalized anxiety 5 patients, panic 2 plus depressive symptoms one patient. did not show disease activity, (10%) (P<0.05). clinically inactive, they lower levels psychological distress (GHQ scale, 1.8 vs 5.6, P<0.001), grade measured by both HA (3.2 8.2, P<0.01) STAI-S (7.95 20.90, P<0.001) scales. We also found score pain perception (VAS-P) (2.80 4.25, P<0. 01) higher occupational activity (83.9 66.2, general functioning (GAS) (93.75 83.50, P<0.05) stage. No significant differences compared cognitive impairment, depression physical disability between stages. conclude that episodes are usually mild seem be related impact on patients. This type pathology is similar which would expected other groups coping stressful event, indicating our react way specifically determined