High Resolution Computed Tomography and Chronic Obstructive Pulmonary Disease

摘要: Chronic obstructive pulmonary disease (COPD) is a preventable and treatable respiratory with some significant extrapulmonary effects that may contribute to the severity in individual patients. Its components are characterized by airflow limitation not fully reversible. COPD leading cause of morbidity mortality worldwide. The economic social burdens due it substantial anticipated increase coming decades continued exposure risk factors changing age profile world’s population. trends generally track several behind smoking trends. In US 2000, more women than men died or its related complications. comprise heterogeneous group disorders conventionally including emphysema, chronic bronchitis, peripheral airways vascular disease. It state has seen changes defining excluding criteria over past 50 years. Spirometry, most frequently used tool diagnose assess response treatment these patients, can provide only functional assessment. contrast spirometry, radiological imaging allows for regional assessment various compartments involved i.e. airways, parenchyma vasculature. High-resolution computed tomography (HRCT) recommended non-invasive sensitive morphological emphysema been shown correlate well pathology. With advent new techniques like multi-detector row CT (MDCT), contrast-enhanced methods, spirometric controlled MDCT, use Xenon gas ventilation lungs, magnetic resonance (MRI) lung developing own arsenal hyperpolarized He-3 MRI – avenues being opened up which now increasingly supplemented advanced dedicated softwares.