microRNA regulation of cancer–endothelial interactions: vesicular microRNAs on the move…
作者： Nils Halberg , Claudio Alarcón , Sohail F Tavazoie
关键词:
摘要: Molecular mechanisms that enable cancer cells to recruit endothelial are intensely studied. Zhuang et al (2012) in this issue of The EMBO Journal describe a new mode communication between and drives migration. authors characterize small non‐coding RNA (microRNA‐9) transfers information from cells. This microRNA is transported microvesicles, functionally facilitating angiogenesis tumour growth.
nature.com
sci-hub.se 参考文章(8)
K Jin Kim, Bing Li, Jane Winer, Mark Armanini, Nancy Gillett, Heidi S Phillips, Napoleone Ferrara, None, Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo Nature. ,vol. 362, pp. 841- 844 ,(1993) , 10.1038/362841A0
Peter Carmeliet, Rakesh K. Jain, Molecular mechanisms and clinical applications of angiogenesis Nature. ,vol. 473, pp. 298- 307 ,(2011) , 10.1038/NATURE10144
Hadi Valadi, Karin Ekström, Apostolos Bossios, Margareta Sjöstrand, James J Lee, Jan O Lötvall, Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells Nature Cell Biology. ,vol. 9, pp. 654- 659 ,(2007) , 10.1038/NCB1596
Li Ma, Jennifer Young, Harsha Prabhala, Elizabeth Pan, Pieter Mestdagh, Daniel Muth, Julie Teruya-Feldstein, Ferenc Reinhardt, Tamer T. Onder, Scott Valastyan, Frank Westermann, Frank Speleman, Jo Vandesompele, Robert A. Weinberg, miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis Nature Cell Biology. ,vol. 12, pp. 247- 256 ,(2010) , 10.1038/NCB2024
Kim J. Png, Nils Halberg, Mitsukuni Yoshida, Sohail F. Tavazoie, A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells Nature. ,vol. 481, pp. 190- 194 ,(2012) , 10.1038/NATURE10661
Guanglei Zhuang, Xiumin Wu, Zhaoshi Jiang, Ian Kasman, Jenny Yao, Yinghui Guan, Jason Oeh, Zora Modrusan, Carlos Bais, Deepak Sampath, Napoleone Ferrara, None, Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway The EMBO Journal. ,vol. 31, pp. 3513- 3523 ,(2012) , 10.1038/EMBOJ.2012.183
Douglas Hanahan, Robert A. Weinberg, Hallmarks of cancer: the next generation. Cell. ,vol. 144, pp. 646- 674 ,(2011) , 10.1016/J.CELL.2011.02.013
Héctor Peinado, Maša Alečković, Simon Lavotshkin, Irina Matei, Bruno Costa-Silva, Gema Moreno-Bueno, Marta Hergueta-Redondo, Caitlin Williams, Guillermo García-Santos, Cyrus M Ghajar, Ayuko Nitadori-Hoshino, Caitlin Hoffman, Karen Badal, Benjamin A Garcia, Margaret K Callahan, Jianda Yuan, Vilma R Martins, Johan Skog, Rosandra N Kaplan, Mary S Brady, Jedd D Wolchok, Paul B Chapman, Yibin Kang, Jacqueline Bromberg, David Lyden, Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET Nature Medicine. ,vol. 18, pp. 883- 891 ,(2012) , 10.1038/NM.2753