Plasmalogens protect unsaturated lipids against UV-induced oxidation in monolayer
作者： Sandrine Morandat , Muriel Bortolato , Geneviève Anker , Alain Doutheau , Michel Lagarde
DOI: 10.1016/J.BBAMEM.2003.08.001
关键词:
摘要: Abstract Oxidative stress results from the attack by free radicals of several cellular targets (proteins, DNA and lipids). The cell equilibrium is a direct consequence pro-/antioxidant balance. In order to understand physiological processes involved in oxidative stress, we followed oxidation unsaturated lipids using biomimetic system: Langmuir monolayers. mode chosen was UV-irradiation lipid model polyunsaturated phospholipid: 1,2-dilinoleoyl-sn-glycero-3-phosphocholine (DLPC). monomolecular film technique used measure membrane rheology before after UV-irradiation. We showed that DLPC led molecular area surface elasticity modulus decrease attests apparition new species at air–water interface. antioxidant effect synthetic plasmalogen (1-O-(1′-(Z)-hexadecenyl)-2-O-oleoyl-sn-glycero-3-phosphocholine or PPLMOPE) tested on DLPC. Indeed, for about 25% mol PPLMOPE mixed DLPC/PPLMOPE monolayers, complete inhibition decreases observed our experimental conditions. Lower quantities delayed but did not prevent
core.ac.uk
elsevier.com
sci-hub.se 参考文章(46)
Daniela REISS, Klaus BEYER, Bernd ENGELMANN, Delayed oxidative degradation of polyunsaturated diacyl phospholipids in the presence of plasmalogen phospholipids in vitro. Biochemical Journal. ,vol. 323, pp. 807- 814 ,(1997) , 10.1042/BJ3230807
O H Morand, R A Zoeller, C R Raetz, Disappearance of plasmalogens from membranes of animal cells subjected to photosensitized oxidation. Journal of Biological Chemistry. ,vol. 263, pp. 11597- 11606 ,(1988) , 10.1016/S0021-9258(18)38001-3
Y. Uemura, T.C. Lee, F. Snyder, A coenzyme A-independent transacylase is linked to the formation of platelet-activating factor (PAF) by generating the lyso-PAF intermediate in the remodeling pathway. Journal of Biological Chemistry. ,vol. 266, pp. 8268- 8272 ,(1991) , 10.1016/S0021-9258(18)92972-8
Martin Rejzek, Miroslav Vacek, Zdeněk Wimmer, A Mild Approach to the Synthesis of sn‐Glycerol 1,2‐Di‐γ‐linolenate 3‐Palmitate Helvetica Chimica Acta. ,vol. 83, pp. 2756- 2760 ,(2000) , 10.1002/1522-2675(20001004)83:10<2756::AID-HLCA2756>3.0.CO;2-I
George L. Gaines, Insoluble Monolayers at Liquid-gas Interfaces ,(1966)
B. Bose, S. Agarwal, SN Chatterjee, Membrane lipid peroxidation by UV-A: mechanism and implications. Biotechnology and Applied Biochemistry. ,vol. 12, pp. 557- 561 ,(1990) , 10.1111/J.1470-8744.1990.TB00129.X
Ming-Kuei Shih, Miao-Lin Hu, Relative roles of metal ions and singlet oxygen in UVA-induced liposomal lipid peroxidation Journal of Inorganic Biochemistry. ,vol. 77, pp. 225- 230 ,(1999) , 10.1016/S0162-0134(99)00205-6
Bipalb Bose, S.N. Chatterjee, Correlation between UVA-induced changes in microviscosity, permeability and malondialdehyde formation in liposomal membrane Journal of Photochemistry and Photobiology B-biology. ,vol. 28, pp. 149- 153 ,(1995) , 10.1016/1011-1344(94)07102-T
J.C. Mazière, J.D. Routier, C. Mazière, R. Santus, L.K. Patterson, Diphenylhexatriene (DPH)-Labeled Lipids as a Potential Tool for Studies on Lipid Peroxidation in Monolayer Films Free Radical Biology and Medicine. ,vol. 22, pp. 795- 802 ,(1997) , 10.1016/S0891-5849(96)00427-3
Tapani Viitala, Jouko Peltonen, UV-Induced Reaction Kinetics of Dilinoleoylphosphatidylethanolamine Monolayers Biophysical Journal. ,vol. 76, pp. 2803- 2813 ,(1999) , 10.1016/S0006-3495(99)77434-5