Alkaloids isolated from Haemanthus humilis Jacq., an indigenous South African Amaryllidaceae: Anticancer activity of coccinine and montanine

作者: S. Van slambrouck , S. Gunawardana , M.J. van Rensburg , P.C. James , J.G. Mochel

DOI: 10.1016/J.SAJB.2019.01.036

关键词:

摘要: Haemanthus humilis Jacq., an indigenous South African Amaryllidaceae, was studied for the first time for its alkaloid content. From the acid extract of its bulbs, albomaculine, incartine, …

参考文章(61)
N.R. Crouch, T.L. Pohl, D.A. Mulholland, E. Ndlovu, J. van Staden, Alkaloids from three ethnomedicinal Haemanthus species: H. albiflos, H. deformis and H. pauculifolius (Amaryllidaceae) South African Journal of Botany. ,vol. 71, pp. 49- 52 ,(2005) , 10.1016/S0254-6299(15)30148-4
Gwendoline Van Goietsenoven, Véronique Mathieu, Florence Lefranc, Alexander Kornienko, Antonio Evidente, Robert Kiss, Narciclasine as well as other Amaryllidaceae isocarbostyrils are promising GTP-ase targeting agents against brain cancers. Medicinal Research Reviews. ,vol. 33, pp. 439- 455 ,(2013) , 10.1002/MED.21253
Alexander Kornienko, Antonio Evidente, Chemistry, biology, and medicinal potential of narciclasine and its congeners. Chemical Reviews. ,vol. 108, pp. 1982- 2014 ,(2008) , 10.1021/CR078198U
Yun-Yun Zhu, Xue Li, Heng-Yi Yu, Yu-Fang Xiong, Peng Zhang, Hui-Fang Pi, Han-Li Ruan, Alkaloids from the bulbs of Lycoris longituba and their neuroprotective and acetylcholinesterase inhibitory activities Archives of Pharmacal Research. ,vol. 38, pp. 604- 613 ,(2015) , 10.1007/S12272-014-0397-2
Masaru Kihara, Lai Xu, Keiji Konishi, Yoshimitsu Nagao, Shigeru Kobayashi, Tetsuru Shingu, Incartine, a biosynthetic intermediate, from the flowers of Lycoris incarnata Heterocycles. ,vol. 34, pp. 1299- 1301 ,(1992) , 10.3987/COM-92-6068
Jerald J. Nair, Johannes van Staden, Pharmacological and toxicological insights to the South African Amaryllidaceae Food and Chemical Toxicology. ,vol. 62, pp. 262- 275 ,(2013) , 10.1016/J.FCT.2013.08.042
L.B. Pagliosa, S.C. Monteiro, K.B. Silva, J.P. de Andrade, J. Dutilh, J. Bastida, M. Cammarota, J.A.S. Zuanazzi, Effect of isoquinoline alkaloids from two Hippeastrum species on in vitro acetylcholinesterase activity Phytomedicine. ,vol. 17, pp. 698- 701 ,(2010) , 10.1016/J.PHYMED.2009.10.003
Gerard P Ahern, 5-HT and the immune system Current Opinion in Pharmacology. ,vol. 11, pp. 29- 33 ,(2011) , 10.1016/J.COPH.2011.02.004