Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis
作者： Glenn T. Furuta , Jörn Karhausen , Sean P. Colgan , Randall S. Johnson , John E. Tomaszewski
DOI: 10.1172/JCI21086
关键词:
摘要: … of proliferation. Careful histological examination and staining with the proliferation marker Ki-… HIF-1 played a protective role in colonic epithelial cells attenuating clinical manifestations of …
dm5migu4zj3pb.cloudfront.net 参考文章(56)
X. Zhang, C.J. Huang, R. Nazarian, T. Ritchie, J.S. de Vellis, E.P. Noble, Isolation of nuclear proteins from human brains BioTechniques. ,vol. 22, pp. 848- 850 ,(1997) , 10.2144/97225BM13
Cormac T. Taylor, Sean P. Colgan, Therapeutic targets for hypoxia-elicited pathways. Pharmaceutical Research. ,vol. 16, pp. 1498- 1505 ,(1999) , 10.1023/A:1011936016833
Mark D. Suski, David Zabel, Vitaly Levin, Heinz Scheuenstuhl, Thomas K. Hunt, Effect of Hypoxic Hypoxia on Transmural Gut and Subcutaneous Tissue Oxygen Tension Advances in Experimental Medicine and Biology. ,vol. 411, pp. 319- 322 ,(1997) , 10.1007/978-1-4615-5865-1_39
Martin Kruschewski, Thomas Foitzik, Alexandra Perez-Cantó, Annette Hũbotter, Heinz Johannes Buhr, Changes of Colonic Mucosal Microcirculation and Histology in Two Colitis Models: An Experimental Study Using Intravital Microscopy and a New Histological Scoring System Digestive Diseases and Sciences. ,vol. 46, pp. 2336- 2343 ,(2001) , 10.1023/A:1012334727509
Scott E. Brodie, New York, New York, USA Survey of Ophthalmology. ,vol. 40, pp. 417- 419 ,(1996) , 10.1016/S0039-6257(96)80075-0
Andrew J. Wakefield, Elizabeth A. Sankey, Amar P. Dhillon, Af M. Sawyerr, Linda More, Rosalind Sim, Robert M. Pittilo, Peter M. Rowles, Mark Hudson, Adam A.M. Lewis, Ron E. Pounder, Granulomatous vasculitis in Crohn's disease. Gastroenterology. ,vol. 100, pp. 1279- 1287 ,(1991) , 10.1016/0016-5085(91)70014-O
Gerald P. Morris, Paul L. Beck, Margaret S. Herridge, William T. Depew, Myron R. Szewczuk, John L. Wallace, Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon Gastroenterology. ,vol. 96, pp. 795- 803 ,(1989) , 10.1016/S0016-5085(89)80079-4
Vortmeyer Ao, Lubensky Ia, Linehan Wm, Zbar B, Chi Jg, Zhuang Z, Park Ws, Lee Jy, Yoo Nj, Jang Jj, Dong Sm, Kim Cs, Loss of Heterozygosity and Somatic Mutations of the VHL Tumor Suppressor Gene in Sporadic Cerebellar Hemangioblastomas Cancer Research. ,vol. 58, pp. 504- 508 ,(1998)
Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang, Steven C. Clifford, Emma C. Vaux, Matthew E. Cockman, Charles C. Wykoff, Christopher W. Pugh, Eamonn R. Maher, Peter J. Ratcliffe, The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis Nature. ,vol. 399, pp. 271- 275 ,(1999) , 10.1038/20459
Philippe Soriano, Generalized lacZ expression with the ROSA26 Cre reporter strain Nature Genetics. ,vol. 21, pp. 70- 71 ,(1999) , 10.1038/5007