The osmotic resistance, and zeta potential responses of human erythrocytes to transmembrane modification of Ca2+ fluxes in the presence of the imposed low rate radiation field of 90Sr.
作者： Victor V. Zhirnov , Igor N. Iakovenko
DOI: 10.3109/09553002.2014.950716
关键词:
摘要: AbstractPurpose: To investigate the effects of imposed low dose rate ionizing field on membrane stability human erythrocytes under modulation transmembrane exchange Ca2+.Materials and methods: Osmotic resistance was determined by a measure haemoglobin released from when placed in medium containing serial dilutions Krebs isotonic buffer. The zeta potential as indicator surface calculated value cellular electrophoretic mobility. irradiation erythrocyte suspensions carried out applying suitable aliquots 90Sr incubation media.Results: Irradiation (1.5–15.0 μGy·h−1) induced reversible increase hyposmotic hemolysis negative charge outer well changed responses these parameters to modification Ca2+ fluxes with calcimycin nitrendipine.Conclusions: Findings indicate that radionuclides (90Sr) modifies bo...
informahealthcare.com参考文章(93)
Strunecká A, Kmonícková E, Potter Bv, Palecek J, el Desouki Ni, Krpejsová L, The effect of inositol 1,4,5-trisphosphate and inositol 1,4,5-trisphosphorothioate on calcium release and membrane skeleton organization in the human red blood cell. Receptor. ,vol. 1, pp. 141- 154 ,(1991)
Trine L Barksmann, Berit I Kristensen, Palle Christophersen, Poul Bennekou, Pharmacology of the human red cell voltage-dependent cation channel; Part I. Activation by clotrimazole and analogues. Blood Cells Molecules and Diseases. ,vol. 32, pp. 384- 388 ,(2004) , 10.1016/J.BCMD.2004.01.011
L Neyses, R Locher, M Stimpel, R Streuli, W Vetter, Stereospecific modulation of the calcium channel in human erythrocytes by cholesterol and its oxidized derivatives Biochemical Journal. ,vol. 227, pp. 105- 112 ,(1985) , 10.1042/BJ2270105
Sofia de Oliveira, Ana S. Silva-Herdade, Carlota Saldanha, Modulation of erythrocyte deformability by PKC activity. Clinical Hemorheology and Microcirculation. ,vol. 39, pp. 363- 373 ,(2008) , 10.3233/CH-2008-1101
Robert J Hunter, Zeta Potential in Colloid Science ,(1981)
Donald Milton Smith, John Mitchell, Aquametry: A treatise on methods for the determination of water ,(1977)
Lu Yang, Dina A. Andrews, Philip S. Low, Lysophosphatidic acid opens a Ca++ channel in human erythrocytes Blood. ,vol. 95, pp. 2420- 2425 ,(2000) , 10.1182/BLOOD.V95.7.2420.007K12_2420_2425
L Lorand, O J Bjerrum, M Hawkins, L Lowe-Krentz, G E Siefring, Degradation of transmembrane proteins in Ca2+-enriched human erythrocytes. An immunochemical study. Journal of Biological Chemistry. ,vol. 258, pp. 5300- 5305 ,(1983) , 10.1016/S0021-9258(18)32571-7
MJ Dewey, JL Brown, FS Nallaseth, Genetic Differences in Red Cell Osmotic Fragility: Analysis in Allophenic Mice Blood. ,vol. 59, pp. 986- 989 ,(1982) , 10.1182/BLOOD.V59.5.986.986
Gülberk Uçar, Başaran Demir, Berna Uluğ, Lipid peroxidation and antioxidant enzyme activities in erythrocytes of type I and II alcoholics. Cell Biochemistry and Function. ,vol. 23, pp. 29- 37 ,(2005) , 10.1002/CBF.1125