Lipid peroxidation and antioxidant enzyme activities in erythrocytes of type I and II alcoholics.
作者： Gülberk Uçar , Başaran Demir , Berna Uluğ
DOI: 10.1002/CBF.1125
关键词:
摘要: Reduced and oxidized glutathione (GSH GSSG), protein-bound glutathione, lipid peroxidation antioxidant enzyme activities were determined in the erythrocyte lysates membranes of type I II alcoholics order to clarify effect age-of-onset duration alcohol consumption on oxidant status. The osmotic fragility susceptibility erythrocytes haemolysis also determined. Erythrocyte was significantly increased but, GSH GSH, GSH/GSSG ratio markedly decreased alcoholic subgroups. count haemoglobin content blood found be accordance with finding that more fragile less resistant particularly alcoholics. present study showed ethanol-induced oxidative stress can lead membrane-specific injuries subtypes.
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