Recent ventricular repolarization markers in resistant hypertension: are they different from the traditional QT interval?

摘要: BACKGROUND: Two electrocardiographic markers of ventricular repolarization abnormalities have been recently proposed: spatial T-wave axis deviation and T(peak)-T(end)-interval duration. The aim this study was to evaluate these in patients with resistant hypertension, particularly their relationships left mass (LVM) geometric patterns, comparison the more traditional marker, QTc interval. METHODS: In a cross-sectional study, 810 hypertensive were evaluated. Clinical, laboratory, electrocardiographic, 24-h blood pressures echocardiographic variables obtained. Maximum duration (Tpe(max)) considered prolonged if it beyond upper quartile value (120 ms), on frontal plane abnormally deviated >105 degrees or < 15 . Statistical analysis involved bivariate tests, multivariate logistic regression covariance. RESULTS: Tpe(max)-interval prolongation, like QTc-interval found be associated body index, systolic pressure (SBP), indexed LVM, serum potassium, heart rate. Abnormal T-axis male gender, presence coronary disease, creatinine, SBP, potassium. All three parameters shown increased after adjustment for possible confounders. However, when included together into same model, only abnormal prolongation remained independently LVM. also concentric hypertrophy pattern. CONCLUSIONS: Both proposed are LVM but appears distinct additive classic Their prognostic values should addressed prospective studies