A histopathological study on diabetic nephropathy -- light and electron microscopic observations.

摘要: A historical review and the present author's study on diabetic nephropathy have been presented. Three characteristic lesions in KW-lesion, namely nodular, exudative doughnut lesion may all be regarded as to caused by severe circulatory disturbance occurring intraglomerular branches of afferent artery. This is considered brought about sudden spasm peripheral portion branches. The diffuse form Bell a slighter type without mesangiolysis. Arteriolar hyalinosis arteriosclerosis and/or atherosclerosis disturbances. most important problem nephropathy, including KW-lesion Bell's form, elucidate mechanism leading occurrence Becker4 found fixation antiactomyosin-antibody mesangial tissue immunofluorescent method. Many studies along this line made, but none are adequate fully explaining involved.