iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human

作者: Daniele Bergamaschi , Yardena Samuels , Nigel J. O'Neil , Giuseppe Trigiante , Tim Crook

DOI: 10.1038/NG1070

关键词:

摘要: We have previously shown that ASPP1 and ASPP2 are specific activators of p53; one mechanism by which wild-type p53 is tolerated in human breast carcinomas is through loss of …

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