Process for the synthesis of (4R-cis)-1,1-dimethylethyl 6-iodomethyl or 6-(phenyl-substituted)sulfonyloxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate

作者: Alan Millar , Donald E. Butler

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摘要: An improved process for the preparation of (4R-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate is described where a hydroxy ester derivative converted in two steps to desired product, as well valuable intermediates used process.

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Bruce D. Roth, Charlotte D. Stratton, Milton L. Hoefle, Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis ,(1985)
Thomas Norman Nanninga, Carl Francis Deering, Alan Millar, Donald Eugene Butler, Bruce David Roth, Novel process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis ,(1989)