Rapid identification of the new anabaenopeptin G from Planktothrix agardhii HUB 011 using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
作者： Marcel Erhard , Hans von Döhren , Peter R. Jungblut
DOI: 10.1002/(SICI)1097-0231(19990315)13:5<337::AID-RCM488>3.0.CO;2-Q
关键词:
摘要: Toxic water blooms from cyanobacteria in lakes and rivers are a worldwide phenomenon. A new technique is presented for the rapid detection of toxic nontoxic blooms. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) was employed to identify mainly peptide metabolites (microcystins, anabaenopeptins, cyanopeptolins, microviridins, microginins aeruginosins) microgram quantities prepared cells within minutes. The spectra show presence peptides strains or simultaneously. compound has been identified using post source decay (PSD) collision induced dissociation (CID) mode. This defined as anabaenoeptin G. potential method screening various secondary metabolite producers products including antibiotics discussed. Copyright © 1999 John Wiley & Sons, Ltd.
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sci-hub.se 参考文章(10)
Martin A. Claydon, Simon N. Davey, Valeria Edwards-Jones, Derek B. Gordon, The rapid identification of intact microorganisms using mass spectrometry Nature Biotechnology. ,vol. 14, pp. 1584- 1586 ,(1996) , 10.1038/NBT1196-1584
Kiyonaga Fujii, Kaarina Sivonen, Kyoko Adachi, Kazuyoshi Noguchi, Hiroshi Sano, Kazuo Hirayama, Makoto Suzuki, Ken-ichi Harada, Comparative study of toxic and non-toxic cyanobacterial products: Novel peptides from toxic Nodularia spumigena AV1 Tetrahedron Letters. ,vol. 38, pp. 5525- 5528 ,(1997) , 10.1016/S0040-4039(97)01192-1
The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1. FEBS Letters. ,vol. 371, pp. 236- 240 ,(1995) , 10.1016/0014-5793(95)00888-G
Kathrin Meiβner, Elke Dittmann, Thomas Börner, Toxic and non-toxic strains of the cyanobacterium Microcystis aeruginosa contain sequences homologous to peptide synthetase genes Fems Microbiology Letters. ,vol. 135, pp. 295- 303 ,(1996) , 10.1111/J.1574-6968.1996.TB08004.X
Marcel Erhard, Hans von Döhren, Peter Jungblut, Rapid typing and elucidation of new secondary metabolites of intact cyanobacteria using MALDI-TOF mass spectrometry Nature Biotechnology. ,vol. 15, pp. 906- 909 ,(1997) , 10.1038/NBT0997-906
Jürgen Weckesser, Cornel Martin, Clemens Jakobi, Cyanopeptolins, depsipeptides from cyanobacteria Systematic and Applied Microbiology. ,vol. 19, pp. 133- 138 ,(1996) , 10.1016/S0723-2020(96)80038-5
Hee Jae Shin, Hisashi Matsuda, Masahiro Murakami, Katsumi Yamaguchi, Anabaenopeptins E and F, Two New Cyclic Peptides from the Cyanobacterium Oscillatoria agardhii (NIES-204) Journal of Natural Products. ,vol. 60, pp. 139- 141 ,(1997) , 10.1021/NP960597P
Ken-ichi Harada, Kiyonaga Fujii, Takayuki Shimada, Makoto Suzuki, Hiroshi Sano, Kyoko Adachi, Wayne W. Carmichael, Two cyclic peptides, anabaenopeptins, a third group of bioactive compounds from the cyanobacteriumAnabaena flos-aquae NRC 525-17 Tetrahedron Letters. ,vol. 36, pp. 1511- 1514 ,(1995) , 10.1016/0040-4039(95)00073-L
David E. Williams, Marcia Craig, Charles F. B. Holmes, Raymond J. Andersen, Ferintoic Acids A and B, New Cyclic Hexapeptides from the Freshwater Cyanobacterium Microcystis aeruginosa Journal of Natural Products. ,vol. 59, pp. 570- 575 ,(1996) , 10.1021/NP960108L
Kunimitsu Kaya, Tomoharu Sano, Oscillamide Y, a chymotrypsin inhibitor from toxic Oscillatoria agardhii Tetrahedron Letters. ,vol. 36, pp. 5933- 5936 ,(1995) , 10.1016/0040-4039(95)01198-Q