Inhibition of Cholesterol Biosynthesis
作者： Philippe Boucher , Hans Gerhard Vogel
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摘要: • Mevalonate kinase forming 5-phosphomevalonic acid from mevalonic Phosphomevalonate 5-pyrophosphomevalonic Pyrophosphomevalonate decarboxylase 3-isopentyl-pyrophosphate Isopentyl-pyrophosphate isomerase 3,3-dimethyl-pyrophosphate 3-isopentylpyrophosphate Dimethylallyltransferase in a two-step process geranyl pyrophosphate 3,3-dimethylpyrophosphate Farnesyl Squalene synthetase squalene farnesyl epoxidase 2,3-oxidosqualene 2,3-Oxidosqualene cyclase lanosterol
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