Randomized, controlled trial comparing clinical outcomes of 3D and 2D laparoscopic surgery for gastric cancer: an interim report.

摘要: In this study, we evaluated the short-term outcomes following three-dimensional (3D) or two-dimensional (2D) laparoscopic surgery for patients with gastric cancer. There is a lack of prospective evidence regarding safety and efficacy 3D versus 2D Therefore, conducted phase III single-center, prospective, randomized, controlled trial to compare We compared operation time, intraoperative blood loss, number lymph node dissections, morbidity, mortality between groups The study registered at ClinicalTrials.gov ID NCT02327481. A total 228 were randomized (3D group 115 cases; 113 cases) January 1, 2015 September 2015. Seven who underwent exploratory operations excluded. Finally, 221 analyzed 109 cases, 112 cases). no significant differences two clinical pathological characteristics, operating time vs. 2D, 184 ± 36 178 ± 37 min, P = 0.288), dissections (36 ± 14 37 ± 13, P = 0.698), first ambulation (2.27 ± 1.60 2.04 ± 0.84, P = 0.18), flatus (3.89 ± 1.49 3.69 ± 1.12, P = 0.255), liquid diet (4.88 ± 1.88 4.79 ± 1.57, P = 0.684), duration postoperative hospital stay (12.52 ± 4.83 12.63 ± 7.32, P = 0.903). complication rates 18.3 16.1%, respectively, P = 0.723. No died during stay. However, loss in was significantly lower than (58 ± 75 78 ± 72 ml, P = 0.047). difference harvested groups; however, may reduce procedure. conclude that safe thus ongoing.